Detalhe da pesquisa
1.
NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs.
Cell
; 186(13): 2783-2801.e20, 2023 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37267949
2.
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.
Cell
; 184(1): 149-168.e17, 2021 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33278357
3.
Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense.
Cell
; 181(3): 674-687.e13, 2020 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32298652
4.
TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines.
Nat Immunol
; 22(7): 829-838, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33963333
5.
IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
Cell
; 173(4): 920-933.e13, 2018 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29576451
6.
IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.
Cell
; 167(2): 382-396.e17, 2016 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27693356
7.
Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer.
Cell
; 162(1): 45-58, 2015 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26095253
8.
The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection.
Nat Immunol
; 16(5): 467-75, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25774715
9.
AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence.
Nature
; 597(7876): 415-419, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34471287
10.
ADAR1 and ZBP1 in innate immunity, cell death, and disease.
Trends Immunol
; 44(3): 201-216, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36710220
11.
Galactosaminogalactan activates the inflammasome to provide host protection.
Nature
; 588(7839): 688-692, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33268895
12.
DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome.
Nature
; 573(7775): 590-594, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31511697
13.
Immune regulator IRF1 contributes to ZBP1-, AIM2-, RIPK1-, and NLRP12-PANoptosome activation and inflammatory cell death (PANoptosis).
J Biol Chem
; 299(9): 105141, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37557956
14.
The 'cytokine storm': molecular mechanisms and therapeutic prospects.
Trends Immunol
; 42(8): 681-705, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34217595
15.
Cutting Edge: Caspase-8 Is a Linchpin in Caspase-3 and Gasdermin D Activation to Control Cell Death, Cytokine Release, and Host Defense during Influenza A Virus Infection.
J Immunol
; 207(10): 2411-2416, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34663620
16.
Single cell analysis of PANoptosome cell death complexes through an expansion microscopy method.
Cell Mol Life Sci
; 79(10): 531, 2022 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36169732
17.
Caspase-6 promotes activation of the caspase-11-NLRP3 inflammasome during gram-negative bacterial infections.
J Biol Chem
; 297(6): 101379, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34740613
18.
DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response.
J Biol Chem
; 296: 100579, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33766561
19.
Innate immunity, cytokine storm, and inflammatory cell death in COVID-19.
J Transl Med
; 20(1): 542, 2022 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36419185
20.
Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion.
PLoS Pathog
; 16(3): e1008364, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32150572